The demographic picture was dominated by young patients. Median age was 17 years, with a range spanning 14 to 62, and 40 of the 66 patients, or 60.6 percent, were younger than 18. Clinical findings at both levels of care told a consistent story. Testicular edema, swelling…
ZG16 overexpression in SW620 colorectal cancer cells suppressed proliferation, migration and invasion, induced apoptosis, reduced CD47 and CD24 expression, and increased macrophage-mediated phagocytosis in vitro.
Two transcription factors, SIX1 and TEAD1, appear to work together to fuel colorectal cancer growth by converging on a shared target gene, CTGF, according to a study published in BMC Medical Genomics. The findings, based on human tissue samples, a mouse xenograft…
Because the article is a review, it synthesizes and organizes existing literature rather than reporting new experimental results from a single study, and its conclusions describe potential directions rather than demonstrated clinical outcomes. On the therapeutic side, the review organizes…
A new Cell Division study reports that the transcription factor PRRX2 activates the CNTN3 gene, promoting epithelial-to-mesenchymal transition, proliferation and metastatic traits in colorectal cancer cell and xenograft models. PRRX2-CNTN3 axis drives EMT and metastasis in colorectal cancer News Source: Nathaniel Bowman. (October…
A cross-sectional study of 105 Iranian colorectal cancer patients found that 54.3% had moderate-to-severe malnutrition and 40% faced critical nutritional risk before surgery.
Researchers report that a small RNA molecule circulating in blood, miR-424-3p, may serve as a non-invasive prognostic marker for colorectal cancer, according to a study published in Discover Oncology on 29 October 2026. The study, led by Lili Gao, Yunfei Si and…
Laboratory and mouse experiments show that the underexpressed gene ENDOD1 suppresses colorectal cancer cell proliferation, migration, and invasion partly by blocking Wnt/beta-catenin signaling. Subject of Research: ENDOD1 as a tumor suppressor in colorectal cancer and its inhibition of Wnt/beta-catenin signaling…
The study also traced the molecular wiring of the axis. According to the authors, AKAP12 scaffolds PKA to phosphorylate CREB1, which drives LMOD1 transcription, and LMOD1 in turn remodels actin to tune tight junctions in colorectal cancer cells and gap junctions in fibroblasts. Single-cell…
Three children transferred to a German liver center after severe bleeding during open biopsy of liver tumors prompted the authors to urge image-guided core needle biopsy as the safer default. Subject of Research: Hemorrhagic complications of open surgical biopsy in…
Testicular checks, skin exams, colon and prostate risk discussions and timing.
An article joins this feed when it matches these terms. Each one is also a search of its own.