Genes contain instructions for making proteins, and a central dogma of biology is that this information flows from DNA to RNA to proteins. But only two percent of the human genome actually encodes proteins; the function of the remaining 98 percent…
Osteoarthritis (OA) is a chronic joint disease and hard to cure at present. Accumulating evidence suggests long noncoding RNA-HOTAIR (lncRNA-HOTAIR) plays important role in OA progression. However, the underlying molecular mechanism of HOTAIR in OA... Thank you for visiting nature.
Every living organism has a genetic code that scientists can read and store digitally. This information, known as Digital Sequence Information (DSI), can be downloaded and used to develop medicines, vaccines, cosmetics, improved crop varieties and other commercial products without…
What doesn’t kill a bacterium makes it stronger. An enzyme that bacteria use to fight off viruses works by targeting not just the virus, but also the bacterium itself. It sends the bacterium into a dormant state and makes it…
A new review highlights the potential of CRISPR–Cas13 for RNA-editing therapies. Discussing the advantages of the effector protein Cas13 over Cas9, they report that CRISPR–Cas13 facilitates RNA knockdown, RNA silencing, RNA splicing, RNA-base editing, and translation regulation. CRISPR–Cas13 has diverse applications like…
Scientists at NOAA Fisheries’ Milford Laboratory in Connecticut, and Fisheries and Oceans Canada’s Pacific Biological Station in British Columbia recently participated in a scientific exchange. It was supported by an Ocean Acidification Collaborative Funding Initiative award to share ocean acidification…
The visual system has limited capacity, and cannot process everything that falls onto the retina. Instead, the brain relies on attention to bring salient details into focus and filter out background clutter. Two recent studies have helped to unravel the…
A long-standing goal of neuroscience is to understand how molecules and cellular structures on a microscale give rise to communication between brain regions at the macroscale. A study published in Nature Neuroscience now identifies, for the first time, hundreds of…
Research led by the Australian Institute of Marine Science has provided new insights into how heat-evolved algae, an energy source for coral, withstand heat stress The findings could lead to approaches to improve coral resilience in a warming climate A…
Researchers from Queen Mary University of London finds that directly activating a key cellular energy sensor extended lifespan in yeast, worms and flies, offering new clues about the biology of ageing. Scientists have taken an important step towards understanding how…
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