Many women are experiencing PMOS and fertility-related concerns at a younger age, leading some to explore options such as in vitro fertilisation (IVF) to conceive. However, IVF may not be necessary for everyone. In certain cases, lifestyle changes, including a…
A new bioinformatics and experimental study identifies twelve candidate genes for polycystic ovary syndrome and shows that the metabolic enzyme NNMT drives ferroptosis in ovarian granulosa cells under androgen excess. Polycystic ovary syndrome affects an estimated 8 to 13 percent of women…
A case-control study of 400 Iranian pregnant women reports associations between variants in the SYNPR, CDH18, and PTGIS genes and gestational diabetes risk, including both risk and protective alleles within PTGIS. Subject of Research: Genetic variants in SYNPR, CDH18, and PTGIS associated with…
A mouse study found that nitazoxanide loaded into chitosan nanoparticles reduced fecal and intestinal Cryptosporidium oocyst counts more than free nitazoxanide, with a non-significant improvement in mortality.
Searching for the mechanism, the investigators found that loss of Myc lowered both the mRNA and protein levels of genes encoding glycerophospholipid metabolic enzymes in the granulosa cells. Metabolite measurements matched this enzymatic downshift: knockout of Myc reduced the pool…
A small Russian case-control study reports preliminary associations between MALAT1 and NEAT1 gene variants and polycystic ovary syndrome risk, with cautious statistical support.
Given that 98% of mammals do not have periods, do you know why humans do? When I ask my menstrual health workshop participants – including doctors – there’s usually a lot of shrugging and shaking of heads. If given multiple choice options, most…
Circle sequencing of ovaries from a rat model of polycystic ovary syndrome identified more than 15,000 extrachromosomal circular DNA molecules, with overall abundance reduced compared with controls.
As an academic medical center, we are able to offer our patients access to clinical trials that are studying new treatments for pelvic floor disorders. This means our patients may have access to new treatments that are not yet widely…
A Dutch survey found that only 3 percent of general practitioners routinely assessed pelvic floor muscles in patients with anorectal complaints, while most professional groups expressed willingness to explore a one-time pelvic floor physical therapy consultation.
Menstrual health, PCOS, endometriosis, fibroids, and pelvic floor support.
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