A study by Leicester researchers shows that the timing of radiotherapy treatment may be as important as how it is given for prostate cancer patients. Researchers at the University of Leicester have discovered that a patient’s genetic makeup and the…
A systematic review of sixteen studies finds that emerging serum and urine protein biomarkers, including PHI, PSP94/PSA ratio, ANXA3 and uromodulin peptides, can complement PSA testing to improve prostate cancer detection and risk stratification. Subject of Research: Emerging serum and urine…
Operational consistency receives detailed attention. The document unifies how patients are prepared before scanning, how radiopharmaceuticals are injected, which scanning protocols are followed, and how reports are written. By aligning these steps across institutions, the guidelines seek to reduce variability…
A commercial AI tool for prostate MRI achieved a numerically higher AUC with its quasi-continuous risk score than with fixed PI-RADS thresholds against biopsy ground truth, but the difference did not reach statistical significance. Subject of Research: Diagnostic performance of…
OncLive Biomarkers in Prostate Cancer: Testing the Right Patients, Reading the Right Report In this OncLive News Network program, genitourinary oncology experts examine how biomarker testing has become central to treatment selection in prostate cancer now that biomarker-defined therapies apply…
A single-case report describes how ⁶⁸Ga-DOTATATE PET/CT localized a mandibular phosphaturic mesenchymal tumor that ¹⁸F-FDG PET/CT showed only faintly, enabling resection that normalized serum phosphate within 15 days. Dual-Tracer PET/CT Pinpoints Rare Tumor Behind Severe Bone Pain Tumor-induced…
A LASSO-based risk score built from oxidative stress-related genes predicts biochemical recurrence in prostate cancer, with LAMP5 knockdown reducing PC3 and DU145 cell proliferation, migration and invasion.
A new review explains how reactive oxygen species shift from essential cellular signals to drivers of prostate cancer, bladder cancer and renal cell carcinoma.
A retrospective cohort study of 124 men with biopsy Gleason 6 prostate cancer found that elevated PSA density and perineural invasion were independently associated with Gleason score upgrading after radical prostatectomy.
The analysis examined men whose biopsies showed Gleason scores of 3+3 or 3+4, corresponding to Grade Groups 1 and 2. More than half had a higher grade identified when their prostate was examined after radical prostatectomy, highlighting the potential for biopsy findings to underestimate…
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