An experimental oral drug reduced pain-related hypersensitivity in rats while showing limited entry into the brain. The results suggest a possible way to treat nerve pain without some of the unwanted effects that make existing medicines difficult to use. The…
Pain affects many of us(Image: urbazon via Getty Images) Feeling sore and achy? From nagging headaches to backache, sadly, for around10 million Brits, pain is an everyday reality. According to research by Combogesic, 84% of us report mild-to-moderate discomfort. While a…
In 1992, Richard Hanbury was in a terrible Jeep accident. His nerve damage was so extensive that doctors gave him only a few years to live. Instead of accepting his fate, he began seeking a solution. Hanbury founded Sana Health, which…
A retrospective cohort study of 171 patients found that ultrasound-guided trigeminal nerve block was associated with fewer marked blood pressure increases during maxillary osteotomy in bimaxillary orthognathic surgery.
A new review details how pH-, enzyme-, and thermo-responsive hydrogel beads and injectable depots could deliver rheumatoid arthritis drugs directly into inflamed joints, though most evidence remains preclinical.
For people living with chronic back pain, even a simple movement can trigger a sudden surge of pain. Now, scientists have discovered that these painful episodes activate a surprising part of the brain, one closely connected to our sense of…
A randomized trial found that 0.15 µg/kg sufentanil with ciprofol reduced intraoperative body movement and supplemental sedative doses during hysteroscopic surgery, but increased respiratory depression compared with 0.1 µg/kg. A randomized trial of 288 patients undergoing elective hysteroscopic surgery has found…
Study Reports Immediate Pain Freedom in 14 of 15 Patients; all Patients Achieved Favorable Pain Outcomes at a Mean Six-Month Follow-Up Trigeminal neuralgia causes sudden, severe, electric shock–like facial pain that can interfere with eating, speaking, and other daily activities. For…
A new narrative review finds that ultrasound guidance improves injection accuracy, tailors treatment to anatomical variation, and supports emerging minimally invasive therapies for de Quervain's tenosynovitis. Ultrasound Takes Center Stage in Treating De Quervain's Tenosynovitis Subject of Research: The role…
Results showed patients who received erector spinae plane block consumed fewer opioids on postoperative day 0 after minimally invasive transforaminal lumbar interbody fusion. Results showed patients who received the erector spinae plane block had reduced opioid consumption on postoperative day 0 compared…
Chronic pain, multimodal strategies, interventional options, and safety concerns.
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